WebThe endoribonuclease IRE1/ERN1 encodes the ER-to-nucleus signaling 1 protein, a human homolog of the yeast Ire1 gene product. In S. cerevisiae, as well as in human, this ER transmembrane IRE serine/threonine protein kinase monitors the status of unfolded proteins inside the ER lumen in response to stress. ... Molecular Weight: The recombinant ... WebSee all IRE1 proteins and peptides Expression system Wheat germ Accession O75460 Protein length Protein fragment Animal free No Nature Recombinant Species Human Sequence EEVINLVDQTSENAPTTVSRDVEEKPAHAPARPEAPVDSMLKDMATIILS TFLLIGWVAFIITYPLSMHQQQQLQHQQFQKELEKIQLLQQQQQQLPFHP Predicted molecular …
IRE1 Inhibitor II The IRE1 Inhibitor II controls the biological ...
WebDec 24, 2024 · IRE1 is the most evolutionarily conserved sensor and is found from yeast to metazoans. Unfolded proteins serve as direct ligands for IRE1’s lumenal sensor domain, promoting its oligomerization and activation in the plane of the ER membrane ( Aragón et al., 2009; Gardner and Walter, 2011; Karagöz et al., 2024; Kimata et al., 2007; Li et al., 2010 ). WebIRE1 alpha is a transmembrane protein that has both serine-threonine kinase and endoribonuclease activities and has a theoretical molecular weight of 110 kDa. When … biokosmetics texas
Ire1 Polyclonal Antibody (600-401-HB9) - thermofisher.com
WebIRE1 alpha is a transmembrane protein that has both serine-threonine kinase and endoribonuclease activities and has a theoretical molecular weight of 110 kDa. When detecting phospho-IRE1 alpha, it is recommended to normalize its band intensity with total IRE1 alpha. References 1. Zheng, W., Xie, W., Yin, D., Luo, R., Liu, M., & Guo, F. (2024). WebThe molecular weight of ubiquitin was 8 kDa. (B) Clofoctol could induce vacuolization of the cytoplasm, although less prominent vacuolization was sometimes observed in cells treated only with sorafenib. Cells treated with clofoctol plus sorafenib showed a significantly greater vacuolization than did cells with either treatment alone. WebMar 9, 2024 · IRE1α Antibody (B-12) is a mouse monoclonal IgG 1 κ IRE1α antibody, cited in 50 publications, provided at 200 µg/ml. raised against amino acids 371-560 of IRE1α of … daily law group newport beach